Product Description: K00135 is a potent and selective inhibitor of PIM kinases. K00135 inhibits survival and clonogenic growth of acute leukemia cells. K00135 inhibits the phosphorylation of PIM downstream targets[1].
Applications: Cancer-Kinase/protease
Formula: C18H18N4O
References: [1]Pogacic V, et al. Structural analysis identifies imidazo [1, 2-b] pyridazines as PIM kinase inhibitors with in vitro antileukemic activity[J]. Cancer research, 2007, 67(14): 6916-6924.
CAS Number: 869650-21-5
Molecular Weight: 306.36
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Pim