Product Description: KB-208 is a phagocytosis inhibitor that acts similarly to intravenous immunoglobulin (IVIG). KB-208 improves immune thrombocytopenia (ITP) in a mouse model at a dose of 1 mg/kg. KB-208 does not affect other blood parameters and does not elevate serum biochemical markers of toxicity, and can be used in research in the field of immunity[1][2].
Formula: C22H23N3O3S
References: [1]Loriamini M, et al. A novel small molecule phagocytosis inhibitor, KB-208, ameliorates ITP in mouse models with similar efficacy as IVIG. Transfusion. 2024 Dec;64(12):2233-2240./[2]Aşık A, et al. Amcasertib Increases Apoptosis While Decreasing Invasive and Migrating Abilities in Breast Cancer Stem Cells[J]. Clinical and Experimental Health Sciences, 2024, 14(3): 800-806.
CAS Number: 1282128-68-0
Molecular Weight: 409.50
Compound Purity: 98.00
Research Area: Inflammation/Immunology
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Others
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