Product Description: KB-R7785 is a novel matrix metalloproteinase (MMP) inhibitor, which improves insulin sensitivity by inhibiting TNF-α production. KB-R7785 can be used for diabetes research. KB-R7785 has a protective efficacy against focal cerebral ischemia[1][2].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C18H27N3O4
References: [1]Morimoto Y, et al. KB-R7785, a novel matrix metalloproteinase inhibitor, exerts its antidiabetic effect by inhibiting tumor necrosis factor-alpha production. Life Sci. 1997;61(8):795-803./[2]Jiang X, et al. Matrix metalloproteinase inhibitor KB-R7785 attenuates brain damage resulting from permanent focal cerebral ischemia in mice. Neurosci Lett. 2001 Jun 1;305(1):41-4.
CAS Number: 168158-16-5
Molecular Weight: 349.42
Research Area: Endocrinology
Solubility: 10 mM in DMSO
Target: MMP
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