L5-DA, CAS 2986876-41-7

Product Description: L5-DA is a G-quadruplex (G4) ligand and selectively stabilized for G4s over ds26. L5-DA exhibits significant cytotoxicity against HeLa cells (IC50=4.3 μM). L5-DA stabilizes G4s in HeLa cells, induces apoptosis, and cell cycle arrest[1].

Applications: Cancer-programmed cell death

Formula: C32H34N6O2

References: [1]Wang Y, et al. A naphthyridine-indole ligand for selective stabilization of G-quadruplexes and conformational conversion of hybrid topology. Bioorg Med Chem. 2021;48:116416.

CAS Number: 2986876-41-7

Molecular Weight: 534.65

Compound Purity: 98.0

Research Area: Cancer

Solubility: DMSO : 25 mg/mL (ultrasonic)

Target: Apoptosis;G-quadruplex

• SKU: MEXHY-144712-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-144712-1
• Package Unit: 1 mg
• Quantity Unit: STK