Product Description: LASSBio-1985 is an NHLd inhibitor (nucleoside hydrolase from Leishmania donovani), with a Ki of 79 μM and an IC50 of 84.6 μM. LASSBio-1985 exhibits selective toxicity against Leishmania parasites, with no toxicity to mammalian cells, making it a promising candidate for research in the field of anti-infective therapies[1].
Applications: COVID-19-immunoregulation
Formula: C18H22N2O7
References: [1]Alves MA, et al. The discovery of a new uncompetitive inhibitor of nucleoside hydrolase from Leishmania donovani. Bioorg Chem. 2025 Mar;156:108209.
Molecular Weight: 378.38
Research Area: Infection
Target: Parasite