Product Description: Lauric acid leelamide is the lauric acid (C-12) amide analog of Leelamine (HY-W005629). Leelamine exhibits inhibitory activity against pyruvate dehydrogenase kinase (PDHK) with an IC50 value of 9.5 µM. Leelamine derivatives possess anti-inflammatory effects and can inhibit phospholipase A2 activity from various sources[1][2].
Formula: C32H53NO
References: [1]Aicher TD, et al. Triterpene and diterpene inhibitors of pyruvate dehydrogenase kinase (PDK). Bioorg Med Chem Lett. 1999 Aug 2;9(15):2223-8./[2]Wilkerson W, et al. Antiinflammatory phospholipase-A2 inhibitors. I[J]. European journal of medicinal chemistry, 1991, 26(7): 667-676.
CAS Number: 2095306-47-9
Molecular Weight: 467.77
Research Area: Inflammation/Immunology
Target: Drug Derivative