Product Description: Ledipasvir D-tartrate is an inhibitor of the hepatitis C virus NS5A, with EC50 values of 34 pM against GT1a and 4 pM against GT1b replicon.
Applications: COVID-19-anti-virus
Formula: C53H60F2N8O12
References: [1]Link JO, et al. Discovery of ledipasvir (GS-5885): a potent, once-daily oral NS5A inhibitor for the treatment of hepatitis C virus infection. J Med Chem. 2014 Mar 13;57(5):2033-46/[2]Hernandez D, et al. Natural prevalence of NS5A polymorphisms in subjects infected with hepatitis C virus genotype 3 and their effects on the antiviral activity of NS5A inhibitors. J Clin Virol. 2013 May;57(1):13-8.
CAS Number: 1502654-87-6
Molecular Weight: 1039.09
Compound Purity: 98.76
Research Area: Infection
Solubility: DMSO : 25 mg/mL (ultrasonic)
Target: HCV