Lobaplatin, CAS 135558-11-1

Lobaplatin, CAS 135558-11-1
SKU
MEXHY-105930-25
Packaging Unit
25 mg
Manufacturer
MedChemExpress

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Product Description: Lobaplatin (D-19466) is a diastereometric mixture of platinum(II) complexe. Lobaplatin arrests cell cycle at G1 and G2/M phase. Lobaplatin induces apoptosis by increasing expressions of caspase and Bax, decreasing expression of Bcl-2. Lobaplatin can be used for research of cancer[1][2][3].

Applications: Cancer-programmed cell death

Formula: C9H18N2O3Pt

References: [1]Du L, et, al. Antitumor activity of Lobaplatin against esophageal squamous cell carcinoma through caspase-dependent apoptosis and increasing the Bax/Bcl-2 ratio. Biomed Pharmacother. 2017 Nov;95:447-452./[2]Wu Q, et, al. Lobaplatin arrests cell cycle progression in human hepatocellular carcinoma cells. J Hematol Oncol. 2010 Oct 31;3:43./[3]McKeage MJ. Lobaplatin: a new antitumour platinum drug. Expert Opin Investig Drugs. 2001 Jan;10(1):119-28.

CAS Number: 135558-11-1

Molecular Weight: 397.33

Compound Purity: 98.0

Research Area: Cancer

Solubility: DMSO : 4.55 mg/mL (ultrasonic;warming;heat to 60°C)/H2O : 50 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Apoptosis;Bcl-2 Family;Caspase
More Information
SKU MEXHY-105930-25
Manufacturer MedChemExpress
Manufacturer SKU HY-105930-25
Package Unit 25 mg
Quantity Unit STK
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