LSD1-IN-20, CAS 1239589-91-3

Product Description: LSD1-IN-20 (compound 1) is a potent dual non-covalent LSD1/G9a inhibitor, with Ki values of 0.44 and 0.68 μM, respectively. LSD1-IN-20 shows antiproliferative activity in THP-1 leukemia cells and MDA-MB-231 breast cancer cells, with IC50 (72 h) of 0.51 and 1.60 μM, respectively[1].

Applications: Cancer-programmed cell death

Formula: C27H38N6O2

References: [1]Menna M, et al. Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models. Eur J Med Chem. 2022 Jul 5;237:114410.

CAS Number: 1239589-91-3

Molecular Weight: 478.63

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Histone Demethylase;Histone Methyltransferase

• SKU: MEXHY-146285-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-146285-10
• Package Unit: 10 mg
• Quantity Unit: STK