MC-25B

Product Description: MC-25B is a specific FKBP12 PROTAC degrader. MC-25B degrades FKBP12 with a DC50 of 0.35 μM and a Dmax of 89%. MC-25B facilitates the degradation of nuclear-localized FKBP12 through a DCAF16-dependent mechanism. (Pink: FKBP12 ligand (HY-170988); Blue: E3 ligase ligand HY-170986); Black: linker (HY-128844); FKBP12 ligand+ linker (HY-170987))[1].

Formula: C65H92ClN7O14

Molecular Weight: 1230.92

Research Area: Cancer

Target: FKBP

• SKU: MEXHY-170983-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170983-0
• Package Unit: Get quote
• Quantity Unit: STK