Product Description: MCTR3 is a potent cytokine of pro-resolving mediating maresin conjugates in tissue regeneration (MCTR), which reduces the inflammatory response and promotes the tissue regeneration. MCTR3 exhibits potency in ameliorating LPS-induced acute lung injury and arthritis[1][2][3].
Applications: COVID-19-immunoregulation
Formula: C25H37NO5S
References: [1]Zhuang R, et al., MCTR3 reduces LPS-induced acute lung injury in mice via the ALX/PINK1 signaling pathway. Int Immunopharmacol. 2021 Jan;90:107142./[2]Dalli J et al., Identification and Actions of a Novel Third Maresin Conjugate in Tissue Regeneration: MCTR3. PLoS One. 2016 Feb 16;11(2):e0149319./[3]Pistorius K, et al., MCTR3 reprograms arthritic monocytes to upregulate Arginase-1 and exert pro-resolving and tissue-protective functions in experimental arthritis. EBioMedicine. 2022 May;79:103974.
CAS Number: 1784701-63-8
Molecular Weight: 463.63
Compound Purity: 98.40
Research Area: Inflammation/Immunology; Others
Solubility: 10 mM in DMSO
Target: Endogenous Metabolite
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