Product Description: Mitochondria modulator-2 (Compound Ir1) induces the depolarization of mitochondrial membrane potential, induces ROS generation, inhibits cell migration of A549, arrests the cell cycle at G2/M phase, and induces apoptosis in A549[1].
Formula: C63H50F12IrN6OP3
References: [1]Fu H, et al., Triphenylphosphine-modified cyclometalated iridiumIII complexes as mitochondria-targeting anticancer agents with enhanced selectivity. Bioorg Chem. 2025 Feb;155:108148.
Molecular Weight: 1420.23
Research Area: Cancer
Target: Apoptosis;Mitochondrial Metabolism;Reactive Oxygen Species