MKA031, CAS 2951012-00-1

Product Description: MKA031 (compound 6y) is a non-competitive MIF inhibitor with an IC50 value of 1.7 μM. MKA031 (compound 6y) interferes with MIF/AIF interaction, MIF nuclear translocation, and N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced dependent cell death. MKA031 can be used in the study of chronic hepatitis C virus infection[1].

Applications: COVID-19-anti-virus

Formula: C21H17N5O2S

References: [1]Chen D, et al. Allosteric Inhibitors of Macrophage Migration Inhibitory Factor (MIF) Interfere with Apoptosis-Inducing Factor (AIF) Co-Localization to Prevent Parthanatos. J Med Chem. 2023 Jul 13;66(13):8767-8781.

CAS Number: 2951012-00-1

Molecular Weight: 403.46

Compound Purity: 98.69

Research Area: Infection

Solubility: DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Macrophage migration inhibitory factor (MIF)

• SKU: MEXHY-149308-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-149308-10
• Package Unit: 10 mg
• Quantity Unit: STK