MKLP2-IN-1, CAS 2929345-46-8

Product Description: MKLP2-IN-1 (compound 12a) is an inhibitor of MKLP2 with good oral bioavailability. MKLP2-IN-1 inhibits the microtubule-stimulated ATPase activity of recombinant MKLP2 in vitro and suppresses tumor growth in a mouse Calu-6 lung cancer model[1].

Applications: Cancer-programmed cell death

Formula: C23H19BrFN3O2

References: [1]Huang J, et al. Discovery of novel, potent and orally available benzoazipinone derivatives that elicit MKLP2-inhibitory phenotypes[J]. European Journal of Medicinal Chemistry Reports, 2024, 11: 100145.

CAS Number: 2929345-46-8

Molecular Weight: 468.32

Research Area: cancer

Target: Kinesin

• SKU: MEXHY-170850-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170850-0
• Package Unit: Get quote
• Quantity Unit: STK