MRE 3008F20, CAS 252979-43-4

Shelf life (days): 1460

Info: An adenosine A3 receptor antagonist (Ki = 0.8 nM for the human receptor); selective for the adenosine A3 receptor over adenosine A1, -A2A, and -A2B receptors (Kis = 1,197, 140, and 2,056 nM, respectively, for the human receptors); inhibits IB-MECA-induced cAMP accumulation in CHO cells expressing the human adenosine A3 receptor (IC50 = 5.2 nM); reverses NECA- or 2-Cl-IB-MECA-induced decreases in NF-κB activation and TNF-α and IL-8 levels in LPS-stimulated primary human osteoarthritic synoviocytes at 1 µM

Formulation: A solid

Formal Name: N-[2-(2-furanyl)-8-propyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-N′-(4-methoxyphenyl)-urea

Purity: ≥95%

Formula Markup: C21H20N8O3

Formula Weight: 432.444

CAS Number: 252979-43-4

• SKU: CAY43169-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 43169-1
• Package Unit: 1 mg
• Quantity Unit: STK