MRT 68601 (hydrochloride), CAS 1962928-25-1

Product Description: MRT 68601 hydrochloride is a TBK1 inhibitor with an IC50 value of 6 nM. MRT 68601 hydrochloride inhibits autophagosome formation in lung cancer cells[1][2].

Applications: Cancer-Kinase/protease

Formula: C25H35ClN6O2

References: [1]Newman AC, et al. TBK1 kinase addiction in lung cancer cells is mediated via autophagy of Tax1bp1/Ndp52 and non-canonical NF-κB signalling. PLoS One. 2012;7(11):e50672./[2]McIver EG, et al. Synthesis and structure-activity relationships of a novel series of pyrimidines as potent inhibitors of TBK1/IKKε kinases. Bioorg Med Chem Lett. 2012 Dec 1;22(23):7169-73.

CAS Number: 1962928-25-1

Molecular Weight: 487.04

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: IKK

• SKU: MEXHY-110341-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-110341-10
• Package Unit: 10 mg
• Quantity Unit: STK