MS21, CAS 2376137-05-0

Product Description: MS21 is an effective AKT PROTAC degrader. MS21 can inhibit mutations in the PI3K/PTEN pathway, suppress the proliferation and induce cell cycle arrest of tumor cells. MS21 has anti-tumor activity. (Pink: AKT ligand-2 (HY-48682); Black: Linker (HY-W014125); Blue: (S,R,S)-AHPC (HY-125845))[1].

Applications: Cancer-programmed cell death

Formula: C58H79ClN12O6S

References: [1]Xu J, et al. AKT Degradation Selectively Inhibits the Growth of PI3K/PTEN Pathway-Mutant Cancers with Wild-Type KRAS and BRAF by Destabilizing Aurora Kinase B. Cancer Discov. 2021 Jul 23.

CAS Number: 2376137-05-0

Molecular Weight: 1107.84

Compound Purity: 99.88

Research Area: Cancer

Solubility: Methanol : 95 mg/mL (ultrasonic)

Target: Akt;PROTACs

• SKU: MEXHY-141807-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-141807-50
• Package Unit: 50 mg
• Quantity Unit: STK