Product Description: MSRV-IN-1 (Compound M3) is an inhibitor targeting aquatic rhabdoviruses (such as MSRV, SVCV and IHNV). Its IC50 values for inhibiting MSRV, SVCV and IHNV are 0.92 μM, 2.92 μM and 2.78 μM respectively. MSRV-IN-1 does not act directly on the virions but rather inhibits viral replication by altering the cell cycle arrest state in the S phase induced by the virus and disrupting the viral replication environment. When administered intraperitoneally at a dose of 20 mg/kg, MSRV-IN-1 can significantly increase the survival rate of largemouth bass infected with MSRV by 35.98% and reduce the viral loads in the liver, spleen and kidney. MSRV-IN-1 can be used in the research of diseases related to rhabdoviruses in aquaculture[1].
Formula: C18H16N2O6
References: [1]Yang F, et al. Efficient antiviral activity of a novel magnolol derivative against aquatic rhabdoviruses[J]. Aquaculture, 2025, 604: 742464.
CAS Number: 1438403-50-9
Molecular Weight: 356.33
Research Area: Infection
Target: DNA/RNA Synthesis
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