mTOR inhibitor-13, CAS 1144075-44-4

Product Description: mTOR inhibitor-13 (compound 9g), an aryl ureido compound, is a potent and selective mTOR inhibitor with an IC50 of 0.29 nM. mTOR inhibitor-13 also inhibits PI3K-α with an IC50 of 119 nM[1].

Applications: Cancer-Kinase/protease

Formula: C24H22N6O2S

References: [1]Jeroen C Verheijen, et al. Discovery of 2-arylthieno[3,2-d]pyrimidines containing 8-oxa-3-azabi-cyclo[3.2.1]octane in the 4-position as potent inhibitors of mTOR with selectivity over PI3K. Bioorg Med Chem Lett. 2010 Jan 1;20(1):375-9.

CAS Number: 1144075-44-4

Molecular Weight: 458.54

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: mTOR;PI3K

• SKU: MEXHY-155211-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-155211-5
• Package Unit: 5 mg
• Quantity Unit: STK