Mutant IDH1-IN-3, CAS 1648909-73-2

Product Description: Mutant IDH1-IN-3 (Compound 1) is a selective allosteric inhibitor of mutant isocitrate dehydrogenase 1 (IDH1). Mutant IDH1-IN-3 has an IC50 of 13 nM for R132H IDH1. Mutant IDH1-IN-3 inhibits the production of D-2-hydroxyglutaric acid (2HG) in cells. Mutant IDH1-IN-3 can be used in the study of cancer[1].

Formula: C22H30N4O

References: [1]Deng G, et al. Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule. J Biol Chem. 2015 Jan 9;290(2):762-74.

CAS Number: 1648909-73-2

Molecular Weight: 366.50

Research Area: Cancer

Target: Isocitrate Dehydrogenase (IDH)

• SKU: MEXHY-100476-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-100476-0
• Package Unit: Get quote
• Quantity Unit: STK