Product Description: Nav1.8-IN-2 (compound 35A) is a potent Nav1.8 inhibitor with an IC50 value of 0.4 nM. Nav1.8-IN-2 can be used for researching pain disorders, cough disorders, and acute and chronic itch disorders[1].
Applications: Neuroscience-Neuromodulation
Formula: C18H13Cl2F3N2O3
References: [1]Sabnis RW. 2-Oxooxazolidine-5-carboxamides as Nav1.8 Inhibitors for Treating Pain Disorders, Cough Disorders, and Acute and Chronic Itch Disorders. ACS Med Chem Lett. 2022;13(3):334-335. Published 2022 Mar 1.
CAS Number: 2756250-30-1
Molecular Weight: 433.21
Research Area: Neurological Disease
Solubility: 10 mM in DMSO
Target: Sodium Channel