NDM-1 inhibitor-7, CAS 26151-73-5

Product Description: NDM-1 inhibitor-7 (Compound A8) is a NDM-1 inhibitor, with IC50 of 10.284 μM. NDM-1 inhibitor-7 restores the ability of MEM to penetrate the cell wall of gram-negative bacteria. NDM-1 inhibitor-7 effectively restores the antibacterial activity of MEM against NDM-1-positive Escherichia coli. NDM-1 inhibitor-7 demonstrates strong efficacy in both the Galleria mellonella infection model and murine peritonitis infection model[1].

Formula: C9H10N2OS2

References: [1]Wang N, et al. Novel methyldithiocarbazate derivatives as NDM-1 inhibitors to combat multidrug-resistant bacterial infection with β-lactams. Bioorg Chem. 2025 Jan;154:108104.

CAS Number: 26151-73-5

Molecular Weight: 226.32

Research Area: Infection; Inflammation/Immunology

Target: Bacterial;Beta-lactamase

• SKU: MEXHY-170835-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170835-0
• Package Unit: Get quote
• Quantity Unit: STK