NDM-1 inhibitor-8

Product Description: NDM-1 inhibitor-8 (Compound 18b) is the covalent inhibitor for new delhi metallo-β-lactamase-1 (NDM-1) with an IC50 of 7.03 μM. NDM-1 inhibitor-8 inhibits the drug resistant strains, exhibits synergistic antibacterial effect with the use of Meropenem (HY-13678). NDM-1 inhibitor-8 exhibits anti-infectious activity in mouse models[1].

Applications: COVID-19-immunoregulation

Formula: C28H23Cl2N3O4SSe

References: [1]Liu W, et al., Development of molecular Trojan horses targeting New Delhi metallo-β-lactamase-1 for the restoration of meropenem susceptibility in drug-resistant bacteria. Eur J Med Chem. 2025 Jan 6;285:117243.

Molecular Weight: 647.43

Research Area: Infection

Target: Bacterial;Beta-lactamase

• SKU: MEXHY-168861-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-168861-0
• Package Unit: Get quote
• Quantity Unit: STK