NE-100 (hydrochloride) (Standard), CAS 149409-57-4

Product Description: NE-100 hydrochloride (Standard) is the analytical standard of NE-100 hydrochloride (HY-101484A). This product is intended for research and analytical applications. NE-100 hydrochloride is an orally active and selective sigma-1 receptor antagonist with an IC50 of 4.16 nM. NE-100 hydrochloride can improve cognitive impairment and has neuroprotective and antipsychotic activities. NE-100 hydrochloride can be used for research on nervous system diseases[1][2].

Formula: C23H34ClNO2

References: [1]Ono Y, et al. A sigma-1 receptor antagonist (NE-100) prevents tunicamycin-induced cell death via GRP78 induction in hippocampal cells. Biochem Biophys Res Commun. 2013 May 17;434(4):904-9./[2]Okuyama S, et al. NE-100, a novel sigma receptor ligand: in vivo tests. Life Sci. 1993;53(18):PL285-90.

CAS Number: 149409-57-4

Molecular Weight: 391.97

Research Area: Neurological Disease

Target: ATF6;Reference Standards;Sigma Receptor

• SKU: MEXHY-101484AR-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-101484AR-0
• Package Unit: Get quote
• Quantity Unit: STK