Nevanimibe hydrochloride (Standard), CAS 133825-81-7

Product Description: Nevanimibe hydrochloride (Standard) is the analytical standard of Nevanimibe hydrochloride. This product is intended for research and analytical applications. Nevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. Nevanimibe hydrochloride inhibits ACAT2 with an EC50 of 368 nM. Nevanimibe hydrochloride induces cell apoptosis and has the potential for adrenocortical cancer[1].

Formula: C27H40ClN3O

References: [1]LaPensee CR, et al. ATR-101, a Selective and Potent Inhibitor of Acyl-CoA Acyltransferase 1, Induces Apoptosis in H295R Adrenocortical Cells and in the Adrenal Cortex of Dogs. Endocrinology. 2016 May;157(5):1775-88.

CAS Number: 133825-81-7

Molecular Weight: 458.08

Research Area: Cancer

Target: Acyltransferase;Apoptosis;Reference Standards

• SKU: MEXHY-100399AR-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-100399AR-0
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• Quantity Unit: STK