NHE-1-IN-2

Product Description: NHE-1-IN-2 (compound 7g) is a potent NHE-1 inhibitor with an IC50 of 0.78 μM. NHE-1-IN-2 alleviates left ventricular systolic dysfunction in mice model of heart failure[1].

Formula: C23H20ClN3O3

References: [1]Cao M, et al. Novel sodium-hydrogen exchanger 1 inhibitors with diphenyl ketone scaffold: Design, Synthesis, mechanism and evaluation in mice model of heart failure. Eur J Med Chem. 2025 Jul 5;291:117585.

Molecular Weight: 421.88

Research Area: Neurological Disease

Target: Na+/H+ Exchanger (NHE)

• SKU: MEXHY-173517-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-173517-0
• Package Unit: Get quote
• Quantity Unit: STK