NIBR-LTSi

Product Description: NIBR-LTSi is an orally active and selective LATS kinase inhibitor. NIBR-LTSi can activate YAP signaling. NIBR-LTSi promotes stem cell proliferation, maintains stemness and blocks differentiation. NIBR-LTSi accelerates liver regeneration following extended hepatectomy in mice[1].

Applications: Cancer-Kinase/protease

Formula: C18H20N4O

References: [1]Namoto K, et al. NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo. Cell Stem Cell. 2024 Apr 4;31(4):554-569.e17.

Molecular Weight: 308.38

Compound Purity: 99.97

Research Area: Others

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: YAP

• SKU: MEXHY-160769-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-160769-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK