Product Description: NLRP3-IN-68 (Compound 2d) is a 1,3,4-oxadiazole derivative. NLRP3-IN-68 has strong anti-inflammatory and antioxidant activities, which can inhibit inflammatory cytokines secretion, iNOS expression and NLRP3 inflammasome activation. NLRP3-IN-68 can be used in the research of anti-inflammatory drugs[1].
Formula: C18H15FN2O3
References: [1]Sun J, et al. Synthesis of bioisosteres of caffeic acid phenethyl ester: 1,3,4-oxadiazole derivatives containing a catechol fragment with anti-inflammatory activities in vitro and in vivo. Bioorg Chem. 2025 Jan 3;155:108123.
Molecular Weight: 326.32
Research Area: Inflammation/Immunology
Target: NO Synthase;NOD-like Receptor (NLR)