NP3-253, CAS 2557349-50-3

Product Description: NP3-253 is an NLRP3 inhibitor with oral activity and blood-brain barrier permeability, and NP3-253 can serve as a tool to further investigate the biological characteristics of NLRP3 in peripheral and neuroinflammatory model[1].

Applications: COVID-19-immunoregulation

Formula: C19H23F3N4O

References: [1]Mackay A, et al. Discovery of NP3-253, a Potent Brain Penetrant Inhibitor of the NLRP3 Inflammasome[J]. Journal of Medicinal Chemistry, 2024.

CAS Number: 2557349-50-3

Molecular Weight: 380.41

Compound Purity: 99.78

Research Area: Inflammation/Immunology; Neurological Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: NOD-like Receptor (NLR)

• SKU: MEXHY-169996-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-169996-50
• Package Unit: 50 mg
• Quantity Unit: STK