NS3736, CAS 265646-94-4

Product Description: NS3736 is an orally effective chloride channel inhibitor that can be used for the research of osteoporosis. NS3736 targets the CIC-7 channel in osteocytes, blocks osteoclast acidification and resorption in vitro, with IC50=30 μM. In a rat model of ovariectomy-induced osteoporosis, NS3736 can enhance bone strength and bone density[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C15H9BrClF3N6O

References: [1]Schaller S, et al. The chloride channel inhibitor NS3736 [corrected] prevents bone resorption in ovariectomized rats without changing bone formation. J Bone Miner Res. 2004 Jul;19(7):1144-53.

CAS Number: 265646-94-4

Molecular Weight: 461.62

Research Area: Metabolic Disease

Target: Chloride Channel

• SKU: MEXHY-164532-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-164532-0
• Package Unit: Get quote
• Quantity Unit: STK