NSC 641396, CAS 605685-94-7

NSC 641396, CAS 605685-94-7
SKU
MEXHY-164497-0
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MedChemExpress

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Product Description: NSC 641396 is a ribonucleotide reductase (RNR) inhibitor with an IC50 value of 1.2 μM. NSC 641396 is also a protein arginine N-methyltransferase 9 (PRMT9) inhibitor. NSC 641396 has antitumor activity[1][2].

Formula: C18H13NO3

References: [1] Tholander F, et al. Discovery of antimicrobial ribonucleotide reductase inhibitors by screening in microwell format. Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):9798-803./[2]Dong H, et al. Targeting PRMT9-mediated arginine methylation suppresses cancer stem cell maintenance and elicits cGAS-mediated anticancer immunity. Nat Cancer. 2024 Apr;5(4):601-624.

CAS Number: 605685-94-7

Molecular Weight: 291.30

Research Area: Cancer

Target: DNA/RNA Synthesis;Histone Methyltransferase
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SKU MEXHY-164497-0
Manufacturer MedChemExpress
Manufacturer SKU HY-164497-0
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