NSD2-IN-1, CAS 2797183-37-8

Product Description: NSD2-IN-1 (compound 38) is a potent and high selective NSD2-PWWP1 (nuclear receptor-binding SET domain 2-PWWP1) inhibitor, with an IC50 of 0.11 μM. NSD2-IN-1 can bind to NSD2-PWWP1 and then affect the expression of genes regulated by NSD2. NSD2-IN-1 induces apoptosis and cell cycle arrest[1].

Applications: Cancer-programmed cell death

Formula: C29H31N5

References: [1]Li N, et al. Structure-Based Discovery of a Series of NSD2-PWWP1 Inhibitors. J Med Chem. 2022 Jun 15.

CAS Number: 2797183-37-8

Molecular Weight: 449.59

Compound Purity: 98.72

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Apoptosis

• SKU: MEXHY-147914-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-147914-50
• Package Unit: 50 mg
• Quantity Unit: STK