NVR 3-778, CAS 1445790-55-5

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 4-fluoro-3-[(4-hydroxy-1-piperidinyl)sulfonyl]-N-(3,4,5-trifluorophenyl)-benzamide

Purity: ≥98%

Formula Markup: C18H16F4N2O4S

Formula Weight: 432.389613

CAS Number: 1445790-55-5

Notes: An HBV capsid assembly modulator; inhibits viral replication of HBV genotypes A-H in HepG2 2.2.15 cells (mean EC50s = 0.2-0.58 µM); inhibits the production of HBsAg, HBeAg, and HBV DNA in a primary human hepatocyte model of de novo HBV infection (EC50s = 4.8, 4.5, and 0.81 µM, respectively); reduces serum levels of HBV DNA in HBV-infected mice with humanized livers at 40 mg/kg twice per day

• SKU: CAY42725-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 42725-10
• Package Unit: 10 mg
• Quantity Unit: STK