NYY-6a

Product Description: NYY-6a is a Ferroptosis inhibitor. NYY-6a shows significant inhibitory activity against RSL3-induced ferroptosis across 786-O and HT-1080 cells with EC50s of 52 and 50 nM, respectively. NYY-6a functions as a radical trapping antioxidant (RTA) with efficacy of diminishing lipid peroxidation comparable to ferrostatin-1 and liproxtatin-1. NYY-6a is potential for ferroptosis related pathologies reasearch[1].

Applications: Metabolism-sugar/lipid metabolism

Formula: C23H22N2O3

References: [1]Wan BW, et al. Discovery of novel benzo[b][1,4]oxazine derivatives as ferroptosis inhibitors. Bioorg Chem. 2025 Mar;156:108201. doi: 10.1016/j.bioorg.2025.108201. Epub 2025 Jan 23.

Molecular Weight: 374.43

Research Area: Metabolic Disease; Neurological Disease

Target: Ferroptosis

• SKU: MEXHY-170959-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170959-0
• Package Unit: Get quote
• Quantity Unit: STK