Ontunisertib, CAS 2647949-48-0

Product Description: Ontunisertib (Example 26) is an inhibitor of TGFβ receptor I/ALK5 (TGFβRI/ALK5), with IC50 values ranging from 100 to 500 nM for TGFβRI and an IC50 value of ≤100 nM for ALK5. Ontunisertib can be used in research on gastrointestinal diseases, as well as diseases and cancers related to fibrotic conditions in the skin and eyes[1].

Formula: C27H21F2N5O

References: [1]Ramón BOSSER ARTAL, et al. Benzylamide derivatives as inhibitors of transforming growth factor-beta receptor i/alk5. Patent. WO2021105317, 2021-06-03.

CAS Number: 2647949-48-0

Molecular Weight: 469.49

Research Area: Metabolic Disease;Cancer

Target: TGF-β Receptor

• SKU: MEXHY-168990-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-168990-0
• Package Unit: Get quote
• Quantity Unit: STK