OSI-413 (free base), CAS 183320-29-8

Product Description: OSI-413 (free base) (CP 373413) is a major metabolite of Erlotinib (HY-50896). Erlotinib (CP-358774) is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR[1][2].

Formula: C21H21N3O4

References: [1]Takuya Ishida, et al. Simultaneous determination of erlotinib and its isomeric major metabolites in human plasma using isocratic liquid chromatography-tandem mass spectrometry and its clinical application. Biomed Chromatogr/[2]Moyer JD, et al. Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase. Cancer Res. 1997, 57(21), 4838-4848.

CAS Number: 183320-29-8

Molecular Weight: 379.41

Research Area: Cancer

Target: Drug Metabolite

• SKU: MEXHY-15661A-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-15661A-0
• Package Unit: Get quote
• Quantity Unit: STK