OSI-7904L, CAS 139987-54-5

Product Description: OSI-7904L (GW1843) is a noncompetitive inhibitor of thymidylate synthase (TS). OSI-7904L is an antifolate compound and a substrate for folylpolyglutamate synthetase. OSI-7904L has cytotoxicity against solid tumor lines, and the toxicity can be selectively blocked by folic acid[1].

Formula: C27H24N4O6

References: [1]Schwartz G, et al. A phase I and pharmacokinetic study of 1843U89, a noncompetitive inhibitor of thymidylate synthase, in patients with advanced solid malignancies. Clin Cancer Res. 2001 Jul;7(7):1901-11.

CAS Number: 139987-54-5

Molecular Weight: 500.50

Research Area: Cancer

Target: Antifolate;Thymidylate Synthase

• SKU: MEXHY-10823-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-10823-0
• Package Unit: Get quote
• Quantity Unit: STK