pan-BET/BD2-IN-1

Product Description: pan-BET/BD2-IN-1 (compound 6b) is a selective extra-terminal (BET) protein inhibitor (BRDT-1 Ki = 1.05 μM and BRD4-1 Ki = 0.68 μM). pan-BET/BD2-IN-1 inhibits MM.1S cancer cell growth with an IC50 of 2.6 μM[1].

Applications: Cancer-programmed cell death

Formula: C27H27N3O6

References: [1]Jiewei Jiang, et al. Macrocyclic dihydropyridine analogs as pan-BET BD2-preferred inhibitors. Eur J Med Chem. 2025 Jun 5:290:117504.

Molecular Weight: 489.52

Research Area: Cancer

Target: Epigenetic Reader Domain

• SKU: MEXHY-173315-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-173315-0
• Package Unit: Get quote
• Quantity Unit: STK