pan-Raf/RTK inhibitor 1, CAS 1980821-53-1

Product Description: Pan-Raf/RTK inhibitor 1 (compound I-16) is a potent pan-Raf inhibitor with IC50 values of 3.49 nM (BRafV600E), 8.86 nM (ARaf), 5.78 nM (BRafWT), and 1.65 nM (CRaf). Pan-Raf/RTK inhibitor 1 exhibits antiproliferative activities against various cancer cell lines and can be utilized in cancer research[1].

Formula: C29H28F3N7O3

References: [1]Zhang Y, et al. Potent Pan-Raf and Receptor Tyrosine Kinase Inhibitors Based on a Cyclopropyl Formamide Fragment Overcome Resistance. J Chem Inf Model. 2017 Jun 26;57(6):1439-1452.

CAS Number: 1980821-53-1

Molecular Weight: 579.57

Research Area: Cancer

Target: Raf

• SKU: MEXHY-169869-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-169869-0
• Package Unit: Get quote
• Quantity Unit: STK