PARP7-IN-22, CAS 2946705-91-3

Product Description: PARP7-IN-22 (XLY-1) is a PARP7 inhibitor with an IC50 of 0.6 nM. PARP7-IN-22 (XLY-1) is orally active, enhances type I interferon signaling in vitro, restores type I interferon signaling, promotes T cell infiltration into tumor tissues, and significantly inhibits tumor growth. PARP7-IN-22 shows promise for research in the field of cancer immunotherapy[1].

Applications: Cancer-Kinase/protease

Formula: C19H22F6N8O2

References: [1]Yang J, et al. Discovery of highly potent PARP7 inhibitors for cancer immunotherapy[J]. Bioorganic Chemistry, 2024, 148: 107469.

CAS Number: 2946705-91-3

Molecular Weight: 508.42

Research Area: Cancer

Target: PARP

• SKU: MEXHY-163719-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163719-5
• Package Unit: 5 mg
• Quantity Unit: STK