PBX-7011 (TFA)

Product Description: PBX-7011 TFA is a derivative of camptothecin (HY-16560), which inhibits expressions of the cancer related survival genes DDX5, Survivin, Mcl-1 and XIAP in cells FaDu, degrades DDX5 proteins and exhibits anticancer activity[1].

Applications: Cancer-programmed cell death

Formula: C26H22F3N3O8

References: [1]Jung DY, et al. Camptothecin derivatives that bind to ddx5 protein and prodrugs thereof. WO2023204631A1. 2023-10-26.

Molecular Weight: 561.46

Compound Purity: 99.11

Research Area: Cancer

Solubility: DMSO : 25 mg/mL (ultrasonic)

Target: Bcl-2 Family;Survivin

• SKU: MEXHY-160438B-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-160438B-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK