PCSK9 autophagic degrader 2, CAS 2974497-11-3

Product Description: PCSK9 autophagic degrader 2 (W6) is a PCSK9 targeted autophagosome, with an DC50 of 20.6 nM. PCSK9 autophagic degrader 2 (W6) demonstrates comparable antiatherosclerosis effect and exhibits a KD of 2.5 μM for LC3B (Pink: PCSK9 ligand HY-176044; Blue: LC3B ligand HY-176045; Black: linker HY-141373)[1].

Formula: C39H41Br2IN4O8S

References: [1]Hongyu Wu, et al. PCSK9 Targeted Autophagosome-Tethering Compounds: Design, Synthesis, and Antiatherosclerosis Evaluation. J Med Chem. 2025 Apr 24;68(8):8190-8207.

CAS Number: 2974497-11-3

Molecular Weight: 1012.54

Research Area: Cancer

Target: ATTECs;PCSK9

• SKU: MEXHY-176043-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-176043-0
• Package Unit: Get quote
• Quantity Unit: STK