PCSK9-IN-23, CAS 2115700-96-2

Product Description: PCSK9-IN-23 (compound 5C) is a potent PCSK9 inhibitor. PCSK9-IN-23 blocks PCSK9 secretion from HepG2 cells, significantly increases LDL receptor (LDLR) expression[1].

Applications: Neuroscience-Neuromodulation

Formula: C22H18F6N2O

References: [1]Lisa Giannessi, et al. Identification of 4-amino-2-Pyridones as new potent PCSK9 inhibitors: From phenotypic hit discovery to in vivo tolerability. Eur J Med Chem. 2023 Dec 20:265:116063.

CAS Number: 2115700-96-2

Molecular Weight: 440.38

Compound Purity: 99.57

Research Area: Cardiovascular Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: PCSK9

• SKU: MEXHY-157434-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-157434-25
• Package Unit: 25 mg
• Quantity Unit: STK