PDE2 inhibitor 6, CAS 2097493-39-3

Product Description: PDE2 inhibitor 6 (Compound 1) is the orally active inhibitor for phosphodiesterase (PDE) that inhibits PDE2A, PDE3B, and PDE10A2 with IC50s of 0.95 nM, 6.17 μM (pIC50=5.21) and 87.1 nM (pIC50=7.06), respectively. PDE2 inhibitor 6 modulates the activity of AMPA receptor, enhance the synaptic plasticity and promotes the learning and memory function in rats models. PDE2 inhibitor 6 can cross blood-brain barrier[1].

Formula: C20H22F2N6O

References: [1]Buijnsters P, et al., [1,2,4]TRIAZOLO[1,5-a]PYRIMIDIN-7-YL COMPOUND. WO2017076900

CAS Number: 2097493-39-3

Molecular Weight: 400.43

Research Area: Neurological Disease

Target: iGluR;Phosphodiesterase (PDE)

• SKU: MEXHY-168966-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-168966-0
• Package Unit: Get quote
• Quantity Unit: STK