PF-05020182, CAS 1354712-92-7

Product Description: PF-05020182 is an orally active opener for Kv7 channel, that activates human Kv7.2/7.3, Kv7.4 and Kv7.3/7.5 with EC50 of 334, 625 and 588 nM, respectively. PF-05020182 exhibits anticonvulsant activity in rats corneal electric shock-induced tonic seizure (MES) models. PF-05020182 is blood-brain barrier (BBB) penetrable[1].

Formula: C18H30N4O4

References: [1]Davoren JE, et al., Discovery of a novel Kv7 channel opener as a treatment for epilepsy. Bioorg Med Chem Lett. 2015 Nov 1;25(21):4941-4944.

CAS Number: 1354712-92-7

Molecular Weight: 366.46

Research Area: Neurological Disease

Target: Potassium Channel

• SKU: MEXHY-108327-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-108327-0
• Package Unit: Get quote
• Quantity Unit: STK