PF-07038124 (hydrochloride), CAS 2415317-57-4

PF-07038124 (hydrochloride), CAS 2415317-57-4
SKU
MEXHY-144683A-10
Packaging Unit
10 mg
Manufacturer
MedChemExpress

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Product Description: PF-07038124 hydrochloride is a PDE4 inhibitor with an IC50 of 0.5 nM for PDE4B2. PF-07038124 hydrochloride shows inhibitory activities against IL-13, IL4, and IFNγ (IC50=125, 4.1, 1.06 nM, respectively). PF-07038124 hydrochloride can be used for research of atopic dermatitis and plaque psoriasis[1][2].

Formula: C18H23BClNO4

References: [1]Boron containing pde4 inhibitors.WO2020070651A1./[2]Eichenfield LF, et al. Efficacy and Safety of PF-07038124 in Patients With Atopic Dermatitis and Plaque Psoriasis: A Randomized Clinical Trial. JAMA Dermatol. 2024 Feb 1;160(2):156-163.

CAS Number: 2415317-57-4

Molecular Weight: 363.64

Research Area: Inflammation/Immunology

Target: Phosphodiesterase (PDE)
More Information
SKU MEXHY-144683A-10
Manufacturer MedChemExpress
Manufacturer SKU HY-144683A-10
Package Unit 10 mg
Quantity Unit STK
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