PF-794, CAS 2056111-45-4

Product Description: PF-794 is a potent, selective and ATP-competitive Traf2- and Nck-interacting kinase (TNIK) inhibitor with an IC50 of 39 nM. PF-794 shows selective for the TNIK family. PF-794 reduces endogenous p120-catenin phosphorylation in cells. PF-794 can be used for teh study of psychiatric disorders[1].

Applications: Neuroscience-Neuromodulation

Formula: C22H20N4O

References: [1]Wang Q, et al. Identification of Phosphorylation Consensus Sequences and Endogenous Neuronal Substrates of the Psychiatric Risk Kinase TNIK. J Pharmacol Exp Ther. 2016 Feb;356(2):410-23.

CAS Number: 2056111-45-4

Molecular Weight: 356.42

Compound Purity: 99.19

Research Area: Neurological Disease

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Ser/Thr Protease

• SKU: MEXHY-122805-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-122805-10
• Package Unit: 10 mg
• Quantity Unit: STK