PF-DcpSi, CAS 2092917-19-4

Product Description: PF-DcpSi is a mRNA decapping scavenger enzyme (DcpS) inhibitor (IC50: 0.11 nM). PF-DcpSi (30 mg/kg,i.p.) ameliorates the disease phenotype in a mice model of spinal muscular atrophy (SMA)[1].

Applications: Neuroscience-Neuromodulation

Formula: C16H12FN5O

References: [1]Gopalsamy A, et al. Design of Potent mRNA Decapping Scavenger Enzyme (DcpS) Inhibitors with Improved Physicochemical Properties To Investigate the Mechanism of Therapeutic Benefit in Spinal Muscular Atrophy (SMA). J Med Chem. 2017 Apr 13;60(7):3094-3108.

CAS Number: 2092917-19-4

Molecular Weight: 309.30

Compound Purity: 98.0

Research Area: Neurological Disease

Target: DNA/RNA Synthesis

• SKU: MEXHY-122604-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-122604-5
• Package Unit: 5 mg
• Quantity Unit: STK