Product Description: Phosphatidylinositol-1,2-dioctanoyl sodium significantly inhibits transmembrane P-gp transport in a reproducible, cell line-independent, and substrate-independent manner. Phosphatidylinositol-1,2-dioctanoyl sodium plays an important role in signal transduction and cell movement[1].
Applications: Cancer-programmed cell death
Formula: C25H46NaO13P
References: [1]Lucas X, et al. Discovery of the inhibitory effect of a phosphatidylinositol derivative on P-glycoprotein by virtual screening followed by in vitro cellular studies. PLoS One. 2013 Apr 9;8(4):e60679. /[2]Lucas X, et al. Discovery of the inhibitory effect of a phosphatidylinositol derivative on P-glycoprotein by virtual screening followed by in vitro cellular studies. PLoS One. 2013 Apr 9;8(4):e60679.
CAS Number: 899827-36-2
Molecular Weight: 608.59
Research Area: cancer
Solubility: 10 mM in DMSO
Target: P-glycoprotein
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