Product Description: PI3K-IN-56 (Compound 1) is an orally active, potent and selective irreversible inhibitor of phosphoinositide 3-kinase (PI3K). PI3K-IN-56 irreversibly blocks the phosphatidylinositol-3,4,5-triphosphate (PIP3) production and downstream AKT signaling pathway. PI3K-IN-56 is promising for research of PI3Kα-driven cancers, such as breast and ovarian cancers[1].
Formula: C28H32F3N9O5
References: [1]Neil Sonin DHAWAN, et al. Crystalline forms and salts of a pi3k inhibitor and methods of making and methods of use thereof. WO2023179771A1. 2023-09-28.
CAS Number: 2633645-58-4
Molecular Weight: 631.61
Research Area: Cancer
Target: Akt;PI3K